Pyridinium chloride → HCID 22768860, compound

HRID 1764658Notes

Reaction equation

HRID 1764658 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([C:12]2[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[O:14][C:13]=2[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)(=[O:11])=[O:10])=[CH:5][CH:4]=1.Cl.N1C=CC=CC=1>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]([S:9]([C:12]2[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[O:14][C:13]=2[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)(=[O:11])=[O:10])=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 22768841HCID 22768841, compound

Product 1

HCID 22768860HCID 22768860, compound

Procedure

3-(4-Methoxyphenylsulfonyl)-2-phenylbenzofuran (1.9 g.) was combined with 12 g. of freshly distilled pyridine hydrochloride and heated at 210° for 3.5 hours. The hot mixture was poured onto an ice-dilute hydrochloric acid mixture and the precipitate formed was collected by filtration and dissolved in chloroform. The chloroform solution was extracted three times with water and then with a saturated sodium chloride solution, refluxed with decolorizing charcoal, filtered and dried (MgSO4). Evaporation of the solvent gave 3-(4-hydroxyphenylsulfonyl)-2-phenylbenzofuran, m.p. 166°-168°.

Workup

  1. customthe precipitate formed
  2. filtrationwas collected by filtration
  3. dissolutiondissolved in chloroform
  4. extractionThe chloroform solution was extracted three times with water
  5. temperaturewith a saturated sodium chloride solution, refluxed with decolorizing charcoal
  6. filtrationfiltered
  7. dry with materialdried (MgSO4)
  8. customEvaporation of the solvent

Sources & evidence

ORD record
ord-8bbbf31c8b4b4f849ea72b73ba8c13e9
Source dataset
uspto-grants-1978_09
Patent number
US04117128

Reaction notes

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