HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-n-Butyl-3-[4-(2,3-epoxypropoxy)phenylsulfonyl]benzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Epibromohydrin | HCID 18430 | — |
| Reactant | 2-n-Butyl-3-(4-hydroxyphenylsulfonyl)benzofuran | HCID 14956364 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-n-Butyl-3-[4-(2,3-epoxypropoxy)phenylsulfonyl]benzofuran | HCID 22768837 | — |
Reaction Steps
2-n-Butyl-3-(4-hydroxyphenylsulfonyl)benzofuran (1.5 g., 0.0045 mol.) was dissolved in 40 ml. of dry acetone containing 2.5 g. (0.018 mol.) of potassium carbonate and 2.46 g. (0.018 mol.) of epibromohydrin. The mixture was refluxed for ca. 16 hours then filtered. The solvent and excess epibromohydrin were removed in vacuo to give 2-n-butyl-3-[4-(2,3-epoxypropoxy)phenylsulfonyl]benzofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04117128 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-5b7709ca6bb14565b04340e0e9d48895 |
| Source note | uspto-grants-1978_09 |