3-Chloropropyl(diethyl)amine → 2-(4-Chlorophenyl)-3-[4-(3-diethylaminopropoxy)phenylsulfonyl]benzofuran
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[S:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)(=[O:15])=[O:14])=[CH:4][CH:3]=1.[CH2:27]([N:29]([CH2:34][CH3:35])[CH2:30][CH2:31][CH2:32]Cl)[CH3:28]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[S:13]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH2:32][CH2:31][CH2:30][N:29]([CH2:34][CH3:35])[CH2:27][CH3:28])=[CH:18][CH:17]=2)(=[O:14])=[O:15])=[CH:6][CH:7]=1Participants
3
Procedure
Reaction of 2-(4-chlorophenyl)-3-(4-hydroxyphenylsulfonyl)benzofuran with 3-diethylaminopropyl chloride according to the procedure of Example 1 gives the title compound.
Sources & evidence
- ORD record
- ord-c542ceeb4b3149488c36da42715cb5aa
- Source dataset
- uspto-grants-1978_09
- Patent number
- US04117128
Reaction notes
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