3-Chloropropyl(diethyl)amine → HCID 22768888, compound

HRID 1764684Notes

Reaction equation

HRID 1764684 reaction equation
FC1C=CC=CC=1C1OC2C=CC=CC=2C=1.C1(C2OC3C=CC=CC=3C=2)C=CC=CC=1.[F:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[C:39]1[O:40][C:41]2[CH:58]=[CH:57][CH:56]=[CH:55][C:42]=2[C:43]=1[S:44]([C:47]1[CH:52]=[CH:51][C:50]([O:53][CH3:54])=[CH:49][CH:48]=1)(=[O:46])=[O:45].[CH2:59]([N:61]([CH2:66][CH3:67])[CH2:62][CH2:63]CCl)[CH3:60]>>[CH2:59]([N:61]([CH2:66][CH3:67])[CH2:62][CH2:63][CH2:54][O:53][C:50]1[CH:51]=[CH:52][C:47]([S:44]([C:43]2[C:42]3[CH:55]=[CH:56][CH:57]=[CH:58][C:41]=3[O:40][C:39]=2[C:34]2[CH:35]=[CH:36][CH:37]=[CH:38][C:33]=2[F:32])(=[O:46])=[O:45])=[CH:48][CH:49]=1)[CH3:60]

Participants

5

Reactant 4

HCID 669183-Chloropropyl(diethyl)amineHCID 35179362-Phenyl-benzofuranHCID 22768834HCID 22768834, compoundHCID 22768918HCID 22768918, compound

Product 1

HCID 22768888HCID 22768888, compound

Procedure

Substitution of 2-(2-fluorophenyl)benzofuran in the procedure of Example 1 for 2-phenylbenzofuran followed by demethylation of the 2-(2-fluorophenyl)-3-(4-methoxyphenylsulfonyl)benzofuran thus formed and reaction of the resulting product with 3-diethylaminopropyl chloride as described therein gives the title compound.

Workup

  1. customthus formed

Sources & evidence

ORD record
ord-981eb7001ae346e5826555547a3f669e
Source dataset
uspto-grants-1978_09
Patent number
US04117128

Reaction notes

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