4-Methoxybenzenesulfonyl chloride → HCID 22768907, compound

HRID 1764687Notes

Reaction equation

HRID 1764687 reaction equation
[CH2:1]([C:8]1[O:9][C:10]2[CH:16]=[CH:15][C:14]([CH2:17][CH3:18])=[CH:13][C:11]=2[CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[O:20][C:21]1[CH:26]=[CH:25][C:24]([S:27](Cl)(=[O:29])=[O:28])=[CH:23][CH:22]=1>>[CH2:1]([C:8]1[O:9][C:10]2[CH:16]=[CH:15][C:14]([CH2:17][CH3:18])=[CH:13][C:11]=2[C:12]=1[S:27]([C:24]1[CH:25]=[CH:26][C:21]([OH:20])=[CH:22][CH:23]=1)(=[O:29])=[O:28])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 74014-Methoxybenzenesulfonyl chlorideHCID 22768840HCID 22768840, compound

Product 1

HCID 22768907HCID 22768907, compound

Procedure

Acylation of 2-benzyl-5-ethylbenzofuran with 4-methoxybenzenesulfonyl chloride followed by demethylation of the product thus formed as previously described gives 2-benzyl-5-ethyl-3-(4-hydroxyphenylsulfonyl)benzofuran.

Workup

  1. customthus formed

Sources & evidence

ORD record
ord-2cd53ac0df6e4f7aa4085390c4feeafc
Source dataset
uspto-grants-1978_09
Patent number
US04117128

Reaction notes

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