HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Ethyl 4-(chloromethyl)-1,2,5-trimethylpyrrole-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Ethyl 4-(hydroxymethyl)-1,2,5-trimethylpyrrole-3-carboxylate | HCID 13051083 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Ethyl 4-(chloromethyl)-1,2,5-trimethylpyrrole-3-carboxylate | HCID 20528801 | — |
Reaction Steps
1.0 g of ethyl 4-(hydroxymethyl)-1,2,5-trimethyl-pyrrole-3-carboxylate is dissolved in 15 ml of benzene and 0.6 g of thionyl chloride is added dropwise and after total addition the reaction mixture is stirred for 3.5 hours at ambient temperature. The benzene is removed in vacuo leaving the gray solid, ethyl 4-(chloromethyl)-1,2,5-trimethylpyrrole-3-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04117152 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-b1dbee1a853e4c73b228567091e90d02 |
| Source note | uspto-grants-1978_09 |