Water → HCID 13019275, compound

Participants

Reaction Steps

p-Aminobenzonitrile (11.8 g., 0.1 mole) and 1-bromohexadecane (15.25 g., 0.05 mole) are dissolved in hexamethylphosphoramide (200 ml.) and heated under nitrogen in an oil-bath maintained at 120° for 22 hours. The reaction mixture is cooled to room temperature and water (50 ml.) is added gradually. The mixture is then chilled in an ice-bath. The precipitate is filtered, washed thoroughly with water and dried. It is then washed repeatedly with hexane and dried; 14.2 g. pale brownish yellow granular solid is obtained as homogeneous product. Crystallization from ether-hexane affords pale yellow prisms, melting point 63°-64° C.

Provenance & Evidence