4-Chloroaniline → HCID 22769691, compound

Participants

Reaction Steps

A mixture of 4-chloroaniline (127.5 g) and 2-chloro-3,5-dinitrobenzotrifluoride (270.5 g.) in toluene (2 l.) was heated under reflux for 16 hours and the hot mixture then filtered. The filtrate was concentrated in vacuo, and the true amounts of toluene removed by co-distillation with industrial methylated spirit, to give a black semi-solid. Extraction of this solid with cyclohexane gave yellow crystals of 2(4-chloroanilino)-3,5-dinitrobenzotrifluoride, melting point 104°-106° C.

Provenance & Evidence