6-Methyl-2-pyridinecarboxaldehyde → HCID 54180332, compound

HRID 1764751Notes

Reaction equation

HRID 1764751 reaction equation
[C:1]1([CH:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:8]2[CH2:14][C:13](=[O:15])[NH:12][NH:11][C:10](=[O:16])[CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:23][C:24]1[N:29]=[C:28]([CH:30]=O)[CH:27]=[CH:26][CH:25]=1>C1C=CC=CC=1>[C:17]1([CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[N:8]2[CH2:14][C:13](=[O:15])[N:11]([N:12]=[CH:30][C:28]3[CH:27]=[CH:26][CH:25]=[C:24]([CH3:23])[N:29]=3)[C:10](=[O:16])[CH2:9]2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 707376-Methyl-2-pyridinecarboxaldehydeHCID 22769787HCID 22769787, compound

Product 1

HCID 54180332HCID 54180332, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Reacting 5-diphenylmethyl-3,7-diketo-1,2-dihydro-1,2,5-triazepine with 6-methylpyridine-2-carboxaldehyde in the presence of benzene at reflux temperature and a reaction time of 4 hours to afford 1-diphenylmethyl-4-(6-methyl-2-pyridylmethyleneamino)-3,5-diketopiperazine;

Workup

  1. temperatureat reflux temperature

Sources & evidence

ORD record
ord-257ce4bb37174a8eb3cc1d48b75baf98
Source dataset
uspto-grants-1978_09
Patent number
US04117225

Reaction notes

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