Formaldehyde → HCID 73743101, compound

HRID 1765019Notes

Reaction equation

HRID 1765019 reaction equation
[CH2:1]([O:8][N:9]=[C:10]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH:11]1[CH2:15][CH2:14][CH2:13][NH:12]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:22]=O>C(O)=O>[CH2:1]([O:8][N:9]=[C:10]([CH:11]1[CH2:15][CH2:14][CH2:13][N:12]1[CH3:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 72451686HCID 72451686, compound

Product 1

HCID 73743101HCID 73743101, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

1.2 g (4.28 mmol) of phenyl(2-pyrrolidinyl)methanone O-benzyloxime in 4 ml of a mixture (1/1) of formic acid and aqueous 37% formaldehyde are introduced into a 50 ml round-bottomed flask equipped with a magnetic stirrer, and the mixture is refluxed for 16 hours.

Workup

  1. customequipped with a magnetic stirrer
  2. temperaturethe mixture is refluxed for 16 hours

Sources & evidence

ORD record
ord-1635e9bc7af3488ea2fca5fa007c6067
Source dataset
uspto-grants-2007_06
Patent number
US07226917B2

Reaction notes

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