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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765132Generated: November 2, 2026

3-Methoxyaniline → HCID 22732443, compound

https://huagongshe.com/reaction/1765132

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyanilineHCID 10824—
Reactant4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidineHCID 1485990—
ProductHCID 22732443HCID 22732443—

Reaction Steps

The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (100 mg, 0.385 mmol) and m-anisidine (43 μl, 0.385 mmol) similar to Example 13 and isolated as a pale yellow solid (38 mg, 29%). 1H NMR (Acetone-d6): 9.61 (d, J=2.4 Hz, 1H), 9.42 (s, 1H), 8.76–8.70 (m, 2H), 7.57–7.53 (m, 2H), 7.39 (s, 1H), 7.36 (s, 1H), 7.15 (s, 1H), 6.79–6.75 (m, 1H), 3.87 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07226927B2
Source datasetuspto-grants-2007_06
ORD IDord-e1e385401048468594932a80cbc147d6
Source noteuspto-grants-2007_06