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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765204Generated: November 1, 2026

3,5-Dimethoxyaniline → HCID 22732517, compound

https://huagongshe.com/reaction/1765204

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DimethoxyanilineHCID 66301—
Reactant4-Chloro-6-methyl-2-(pyridin-2-yl)pyrimidineHCID 2763395—
ProductHCID 22732517HCID 22732517—

Reaction Steps

The title compound was prepared from a mixture of 4-chloro-6-methyl-2-(2-pyridinyl)pyrimidine (50 mg, 0.243 mmol) and 3,5-dimethoxyaniline (56 mg, 0.365 mmol) similar to Example 92 and isolated as a tan solid (21 mg, 26%). 1H NMR (CDCl3): 8.83–8.81 (m, 1H), 8.49–8.46 (m, 1H), 7.86–7.80 (m, 1H), 7.39–7.35 (m, 1H), 6.99 (s, 1H), 6.70 (s, 1H), 6.53 (d, J=2.4 Hz, 2H), 6.30 (t, J=2.3 Hz, 1H), 3.82 (s, 6H), 2.51 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07226927B2
Source datasetuspto-grants-2007_06
ORD IDord-2776d27c815848e7b6cd77ed422bd8ac
Source noteuspto-grants-2007_06