HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2,5-dimethoxyaniline → HCID 22732401, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2,5-dimethoxyaniline | HCID 22833 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 22732401 | HCID 22732401 | — |
Reaction Steps
The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 4-chloro-2,5-dimethoxyaniline (54 mg, 0.290 mmol) similar to Example 117 and isolated as a brown solid (52 mg, 63%). 1H NMR (CDCl3): 9.66–9.64 (m, 1H), 8.76–8.71 (m, 2H), 8.35 (s, 1H), 7.54 (s, 1H), 7.45–7.41 (m, 1H), 7.01 (s, 1H), 6.92 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226927B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-7695b31dd6bd4199b8132b82ce14d048 |
| Source note | uspto-grants-2007_06 |