HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloro-5-methoxyaniline → HCID 22732365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloro-5-methoxyaniline | HCID 1476636 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 22732365 | HCID 22732365 | — |
Reaction Steps
The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 2,4-dichloro-5-methoxyaniline (44 mg, 0.232 mmol) similar to Example 117 and isolated as a brown solid (9 mg, 11%). 1H NMR (CDCl3): 9.64–9.63 (m, 1H), 8.76–8.70 (m, 2H), 8.12 (s, 1H), 7.49 (s, 1H), 7.46–7.41 (m, 2H), 6.95 (s, 1H), 4.00 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226927B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-3597df50bdec4024bed5f55dbc133c7c |
| Source note | uspto-grants-2007_06 |