HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-methoxyaniline → HCID 22732360, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-methoxyaniline | HCID 66763 | — |
| Reactant | 4-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485989 | — |
| Product | HCID 22732360 | HCID 22732360 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-(4-pyridinyl)-6-trifluoromethyl-pyrimidine (150 mg, 0.578 mmol) and 5-chloro-2-methoxyaniline (98 mg, 0.621 mmol) similar to Example 160 and was isolated as off-white solid (84 mg, 0.221 mmol, 38%). 1H NMR (CDCl3/MeOH-d4): 8.72 (d, J=4.2 Hz, 2H), 8.51 (s, 1H), 8.34 (d, J=4.5 Hz), 7.09 (m, 2H), 6.91 (d, J=8.4 Hz, 1H), 3.93 (s, 3H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226927B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-83fff85e28ba43029d0110a344688276 |
| Source note | uspto-grants-2007_06 |