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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765278Generated: November 3, 2026

3-Amino-4-methoxybenzoic acid → HCID 22732396, compound

https://huagongshe.com/reaction/1765278

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-methoxybenzoic acidHCID 17823—
Reactant4-Chloro-2-(2-pyrazinyl)-6-(trifluoromethyl)pyrimidineHCID 22732367—
ProductHCID 22732396HCID 22732396—

Reaction Steps

The title compound was prepared from 4-chloro-2-(2-pyrazinyl)-6-trifluoromethylpyrimidine (40 mg, 0.154 mmol) and 5-carboxy-2-methoxyaniline (38 mg, 0.231 mmol), similar to Example 180 and was isolated as an off white solid (20 mg, 33%). 1H NMR (CDCl3): 9.99 (brs, 1H), 9.660 (d, J=1.5 Hz, 1H), 8.86 (m, 3H), 7.80 (d, 2H), 7.2 (m, 2H), 3.94 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07226927B2
Source datasetuspto-grants-2007_06
ORD IDord-2ba0342c03cb4a069f692c5ece0a5b9f
Source noteuspto-grants-2007_06