HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine → HCID 9969316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Reactant | 5-Amino-2-methylindole | HCID 2733992 | — |
| Product | HCID 9969316 | HCID 9969316 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-trifluoromethylpyrimidine (50 mg, 0.192 mmol) and 5-amino-2-methylindole (41 mg, 0.288 mmol) similar to Example 190 and was isolated as a solid. 1H NMR (CDCl3): 9.66 (s, 1H), 8.75–8.72 (m, 2H), 8.08 (s, 1H), 7.46–7.34 (m, 4H), 7.10 (d, J=8.4 Hz, 1H), 6.78 (s, 1H), 6.45 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226927B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-fe22ce88d00948448539460360145282 |
| Source note | uspto-grants-2007_06 |