HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzimidazole → HCID 11401616, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzimidazole | HCID 5798 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-Bromofuran-2-carbaldehyde | HCID 600328 | — |
| Catalyst | HCID 86600327 | HCID 86600327 | — |
| Product | HCID 11401616 | HCID 11401616 | — |
Reaction Steps
Benzimidazole is mixed with 5-bromo-furan-2-yl formaldehyde in the presence of CuI/N,N′-dimethylethylenediamine and cesium carbonate. The resulting [5-(benzimidazol-1-yl)-furan-2-yl]-formaldehyde is purified, then reduced to the title compound with sodium borohydride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226941B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-8515d534edc843ae8c9111d544ef0f7d |
| Source note | uspto-grants-2007_06 |