2-[4-(2,6-difluoro-phenoxy)-6-oxo-6H-pyridazin-1-yl]-3-phenyl-propionic acid → 2-[4-(2,6-difluoro-phenoxy)-6-oxo-6H-pyridazin-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-3-phenyl-propionamide
Reaction equation
[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][n:7][n:8]([CH:12]([C:13](=[O:14])[OH:15])[CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[c:9](=[O:11])[cH:10]2)[c:23]([F:27])[cH:24][cH:25][cH:26]1.[NH2:28][c:29]1[n:30][n:31]([CH2:34][C:35]([CH3:36])([OH:37])[CH3:38])[cH:32][cH:33]1>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][n:7][n:8]([CH:12]([C:13](=[O:14])[NH:28][c:29]3[n:30][n:31]([CH2:34][C:35]([CH3:36])([OH:37])[CH3:38])[cH:32][cH:33]3)[CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[c:9](=[O:11])[cH:10]2)[c:23]([F:27])[cH:24][cH:25][cH:26]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3c9ced79e7574353963231ab49e7b941
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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