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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765481Generated: October 30, 2026

Methanol → HCID 21900164, compound

https://huagongshe.com/reaction/1765481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantIsobutyric AcidHCID 6590—
ReactantTetrabutylammonium HydroxideHCID 2723671—
ProductHCID 21900164HCID 21900164—

Reaction Steps

Alternatively, a 1 M solution of tetrabutylammonium hydroxide in methanol (1 L, 1 mol) and isobutyric acid (88.5 g, 1 mol) was stirred at ambient temperature for 30 min. The solvent was removed in vacuo to afford the title compound (5) as a waxy solid, which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07227028B2
Source datasetuspto-grants-2007_06
ORD IDord-65b1355f882c4a79960987cd0d22462d
Source noteuspto-grants-2007_06