HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-chlorobenzophenone → N-[4-(2-Benzoyl-4-chloro-phenylsulfamoyl)-2-chloro-phenyl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-chlorobenzophenone | HCID 12870 | — |
| Reactant | 3-Chloro-4-acetamidobenzene-1-sulfonyl chloride | HCID 282749 | — |
| Product | N-[4-(2-Benzoyl-4-chloro-phenylsulfamoyl)-2-chloro-phenyl]-acetamide | HCID 11465411 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 115 mg of (2-amino-5-chloro-phenyl)-phenyl-methanone and 133 mg of 4-acetylamino-3-chloro-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 2.24 (s, 3H), 7.36 (d, 1H, J=2.4), 7.40–7.60(m, 8H), 7.66 (d, 1H, J=2.0 Hz), 7.71 (d, 1H, J=8.8 Hz), 8.36 (d, 1H, J=8.8 Hz), 9.63 (s, 1H). MS: m/z 463.0 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07227035B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-02fa6af5e6084c8fb3033cb0b00ba54a |
| Source note | uspto-grants-2007_06 |