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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 176579Generated: October 30, 2026

2-Methoxyethylamine → 6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(2-methoxy-ethyl)-nicotinamide

https://huagongshe.com/reaction/176579

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethylamineHCID 8018—
Reactant1,4-DioxaneHCID 31275—
ReactantTrimethylaluminumHCID 16682925—
Reactant6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl esterHCID 66718164—
Product6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(2-methoxy-ethyl)-nicotinamideHCID 46929060—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-e06e3522fbba417e95c81a146f89793d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)