Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765936Generated: November 2, 2026

O-Methyl-L-Tyrosine → (S)-2-(Biphenyl-3-ylamino)-3-(4-methoxy-phenyl)-propionic acid

https://huagongshe.com/reaction/1765936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-Methyl-L-TyrosineHCID 2723935—
Reactant(S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acidHCID 11384247—
Product(S)-2-(Biphenyl-3-ylamino)-3-(4-methoxy-phenyl)-propionic acidHCID 67492714—

Reaction Steps

The title compound is prepared as described for (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid (example 1) but using O-methyl-L-tyrosine (Bachem). Purification by MPLC (CH3CN/H2O/TFA) afforded the title compound; ES-MS: 348.3 [M+H]+; HPLC: single peak at tR=9.52 min (System 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07229617B2
Source datasetuspto-grants-2007_06
ORD IDord-eadcce4e55f3406fa81f230bb9ed9991
Source noteuspto-grants-2007_06