HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid → (S)-2-(Biphenyl-3-ylamino)-3-(2,3,4-trimethoxyphenyl)-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid | HCID 11384247 | — |
| Reactant | (S)-2-Amino-3-(2,3,4-trimethoxy-phenyl)-propionic acid | HCID 28182480 | — |
| Product | (S)-2-(Biphenyl-3-ylamino)-3-(2,3,4-trimethoxyphenyl)-propionic acid | HCID 67492532 | — |
Reaction Steps
The title compound is prepared as described for (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid (example 1) but using (S)-2-Amino-3-(2,3,4-trimethoxy-phenyl)-propionic acid. Purification by MPLC (CH3CN/H2O/TFA) afforded the title compound; ES-MS: 408.2 [M+H]+; HPLC: single peak at tR=9.42 min (System 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07229617B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-f51d5cb3cc1a436a9abfe728d4dc3279 |
| Source note | uspto-grants-2007_06 |