1-(1,2,3,4-tetrahydroquinolin-6-yl)ethanone → HCID 21108171, compound

HRID 1766030Notes

Reaction equation

HRID 1766030 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[NH:10][CH2:9][CH2:8][CH2:7]2)(=[O:3])[CH3:2].[CH3:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]2[CH:29]=[CH:28][C:24]([C:25](O)=[O:26])=[CH:23][N:22]=2)=[CH:17][CH:16]=1>>[CH3:14][C:15]1[CH:16]=[CH:17][C:18]([C:21]2[N:22]=[CH:23][C:24]([C:25]([N:10]3[C:11]4[C:6](=[CH:5][C:4]([C:1](=[O:3])[CH3:2])=[CH:13][CH:12]=4)[CH2:7][CH2:8][CH2:9]3)=[O:26])=[CH:28][CH:29]=2)=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 104196901-(1,2,3,4-tetrahydroquinolin-6-yl)ethanoneHCID 202218396-(4-Methylphenyl)pyridine-3-carboxylic acid

Product 1

HCID 21108171HCID 21108171, compound

Procedure

Using 6-acetyl-1,2,3,4-tetrahydroquinoline and 6-(4-methylphenyl)nicotinic acid, 1-[1-[[6-(4-methylphenyl)-3-pyridinyl]carbonyl]-1,2,3,4-tetrahydro-6-quinolinyl]ethanone was obtained as pale yellow powder by the same procedure as in Reference Example 5.

Sources & evidence

ORD record
ord-4ac332504fca4da1abe76053076fc0e4
Source dataset
uspto-grants-2007_06
Patent number
US07229986B2

Reaction notes

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