Ethyl Thioglycolate → HCID 69037797, compound

Participants

Reaction Steps

DIPEA (8.71 ml) was added to a stirred solution of ethyl 2-mercaptoacetate (5.15 ml) and 6-chloro-5-cyano-4-(3-nitrophenyl)-2-phenyl-pyrimidine (example 31(b), 15.8 g) in a mixture of EtOH (125 ml) and DCM (125 ml)-under a nitrogen atmosphere. After 2 h at room temperature, the mixture was diluted with DCM until complete dissolution, washed with 0.5N aq. HCl, dried (MgSO4) and concentrated under reduced pressure.

Provenance & Evidence