HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium chloride → 1-Propyl-7-methyl-3-(1-methylpiperdin-4-yl)-5-hydroxy-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | 1-propyl-5-methoxy-7-methyl-3-(1-methylpiperdin-4-yl)-1H-indole | HCID 69432443 | — |
| Product | 1-Propyl-7-methyl-3-(1-methylpiperdin-4-yl)-5-hydroxy-1H-indole | HCID 69435158 | 87.1% |
Reaction Steps
By a method similar to PREPARATION 8, using 1-propyl-5-methoxy-7-methyl-3-(1-methylpiperdin-4-yl)-1H-indole (1.24 g) and pyridine hydrochloride (25 g) to afford 1.03 g (87%) of the title compound: mass spectrum (ion spray): m/z=287 (M+1); Calculated for C18H26N2O.0.4 H2O: C, 73.63; H, 9.34; N, 9.23. Found: C, 73.70; H, 9.34; N, 9.33.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07230011B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-e86e4b4ce387466588edd0a11fa1c770 |
| Source note | uspto-grants-2007_06 |