HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → HCID 10271364, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 17980111 | HCID 17980111 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10271364 | HCID 10271364 | 24.2% |
Reaction Steps
By a method similar to Example 31, using 2-methyl-3-(1-methylpiperidin-4-yl)-5-hydroxy-1H-indole (250 mg, 1.03 mmol), benzenesulfonyl chloride (0.22 g, 1.25 mmol), 0.2N sodium hydroxide and THF (2 mL) gave 96 mg (24%) of the title compound: mass spectrum (ES+)=385.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07230011B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-e284f6d6062a406eb1a5894ae0fd7a73 |
| Source note | uspto-grants-2007_06 |