HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-(4-chloro-2-methyl-benzothiazol-5-yl)-3-methoxy-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | m-Anisoyl chloride | HCID 74374 | — |
| Reactant | 4-Chloro-2-methylbenzo[d]thiazol-5-amine | HCID 11217857 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(4-chloro-2-methyl-benzothiazol-5-yl)-3-methoxy-benzamide | HCID 21110275 | 84% |
Reaction Steps
Reaction of 4-chloro-2-methyl-benzothiazol-5-ylamine (50 mg, 0.25 mmol) in THF (1.5 mL) with m-anisoyl chloride (41 μL, 0.30 mmol) in presence of triethylamine (42 μL, 0.30 mmol) according to method A gave N-(4-chloro-2-methyl-benzothiazol-5-yl)-3-methoxy-benzamide (70 mg, 0.21 mmol, 84% yield) as a orange powder after crystallisation in hexane/DCM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07230020B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-8e566e78d6f54ebaac5c93ca394848a5 |
| Source note | uspto-grants-2007_06 |