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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766340Generated: October 30, 2026

p-Aminoacetophenone → HCID 21110329, compound

https://huagongshe.com/reaction/1766340

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantTriethylamineHCID 8471—
Reactant4-Propylbenzoyl chlorideHCID 104293—
SolventTetrahydrofuranHCID 8028—
ProductHCID 21110329HCID 2111032978.6%

Reaction Steps

Reaction of 4-aminoacetophenone (76 mg, 0.56 mmol) in THF (6 mL) with 4-propylbenzoyl chloride (100 μL, 0.65 mmol) in presence of triethylamine (90 μL, 0.65 mmol) according to method A gave N-(4-acetyl-phenyl)-4-propyl-benzamide (125 mg, 0.44 mmol, 78% yield) as a white powder after washing by dichloromethane and hexane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07230020B2
Source datasetuspto-grants-2007_06
ORD IDord-65f1888e2651463d952bc70a84732300
Source noteuspto-grants-2007_06