Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766343Generated: November 2, 2026

p-Aminoacetophenone → HCID 668715, compound

https://huagongshe.com/reaction/1766343

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantTriethylamineHCID 8471—
Reactantm-Anisoyl chlorideHCID 74374—
SolventTetrahydrofuranHCID 8028—
ProductHCID 668715HCID 66871577.4%

Reaction Steps

Reaction of 4-aminoacetophenone (72 mg, 0.53 mmol) in THF (6 mL) with m-anisoyl chloride (90 μL, 0.65 mmol) in presence of triethylamine (90 μL, 0.65 mmol) according to method A gave N-(4-acetyl-phenyl)-3-methoxy-benzamide (110 mg, 0.41 mmol, 77% yield) as a white powder after washing by dichloromethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07230020B2
Source datasetuspto-grants-2007_06
ORD IDord-6adfbbec92794e8bac579ce2f338eea6
Source noteuspto-grants-2007_06