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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766447Generated: October 30, 2026

1-Pentanol → HCID 11951298, compound

https://huagongshe.com/reaction/1766447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PentanolHCID 6276—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
Reactant(2,4-Dichlorophenyl)boronic acidHCID 2734659—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 11951298HCID 11951298—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 11, using 5-bromo-6-chloro-nicotinic acid methylester, pentanol (commercially available), 2,4-dichlorophenyl-boronic acid (commercially available) and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (m/e): 451.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07229999B2
Source datasetuspto-grants-2007_06
ORD IDord-3ce6e4ccd3dc43948f995476f3c56f52
Source noteuspto-grants-2007_06