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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766449Generated: October 29, 2026

Cyclopropanemethanol → HCID 11951300, compound

https://huagongshe.com/reaction/1766449

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanolHCID 75644—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
Reactant(2,4-Dichlorophenyl)boronic acidHCID 2734659—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 11951300HCID 11951300—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 11, using 5-bromo-6-chloro-nicotinic acid methylester, cyclopropyl-methanol (commercially available), 2,4-dichlorophenyl-boronic acid (commercially available), and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (m/e): 435.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07229999B2
Source datasetuspto-grants-2007_06
ORD IDord-b0076c6fe10e4ba684091ae5eb9e9f54
Source noteuspto-grants-2007_06