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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766484Generated: October 31, 2026

Isopropylethanediol → HCID 11952200, compound

https://huagongshe.com/reaction/1766484

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylethanediolHCID 7996—
Reactant4-Fluorophenylboronic acidHCID 285645—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 11952200HCID 11952200—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 23, using 5-bromo-6-chloro-nicotinic acid methyl ester, 2-isopropoxy-ethanol (commercially available), 4-fluorophenylboronic acid (commercially available) and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (m/e): 417.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07229999B2
Source datasetuspto-grants-2007_06
ORD IDord-0c8a8cbc42f843ac82dcdbe54d2b5f23
Source noteuspto-grants-2007_06