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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766486Generated: October 31, 2026

(2-Methoxyethyl)(methyl)amine → HCID 11952202, compound

https://huagongshe.com/reaction/1766486

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Methoxyethyl)(methyl)amineHCID 300977—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
ReactantMethyl 5-bromo-6-chloronicotinateHCID 2764313—
ProductHCID 11952202HCID 11952202—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 23, using 5-bromo-6-chloro-nicotinic acid methyl ester, (2-methoxy-ethyl)-methyl-amine (commercially available), 4-trifluoromethyl-phenylboronic acid (commercially available) and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (m/e): 452 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07229999B2
Source datasetuspto-grants-2007_06
ORD IDord-955322ef33924984b5a252e669d1a1ea
Source noteuspto-grants-2007_06