HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dioxolane-4-methanol → HCID 11952203, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dioxolane-4-methanol | HCID 21618 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | (1R,2R)-2-Aminocyclohexanol | HCID 735777 | — |
| Reactant | Methyl 5-bromo-6-chloronicotinate | HCID 2764313 | — |
| Product | HCID 11952203 | HCID 11952203 | — |
Reaction Steps
The title compound was synthesized in analogy to the procedure described for the preparation of Example 23, using 5-bromo-6-chloro-nicotinic acid methyl ester, [1,3]dioxolan-4-yl-methanol (commercially available), 4-chlorophenylboronic acid (commercially available) and (1R,2R)-2-amino-cyclohexanol (commercially available) as starting materials. MS (m/e): 433.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07229999B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-4dc7ed71575443f9b49f6e545c864116 |
| Source note | uspto-grants-2007_06 |