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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766491Generated: October 30, 2026

Isoamyl Alcohol → HCID 11952380, compound

https://huagongshe.com/reaction/1766491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoamyl AlcoholHCID 31260—
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant5-Bromo-6-chloropyridine-3-carboxylic acidHCID 285433—
ReactantCyclohexanol, 2-amino-, hydrochloride (1:1), (1R,2R)-HCID 12228412—
ProductHCID 11952380HCID 11952380—

Reaction Steps

The title compound was synthesized in analogy to Example 75, using 5-bromo-6-chloro-3-pyridinecarboxylic acid, 3-methyl-butanol, (4-chloro-phenyl)-boronic acid and (1R,2R)-2-amino-cyclohexanol hydrochloride as starting materials to yield 5-(4-chloro-phenyl)-N-((1R,2R)-2-hydroxy-cyclohexyl)-6-(3-methyl-butoxy)-nicotinamide. MS (ISP) 417.5 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07229999B2
Source datasetuspto-grants-2007_06
ORD IDord-d76936984e9b4b45a3cab0f8d32bbc4e
Source noteuspto-grants-2007_06