HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethanol → HCID 21109684, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | Methyl 5-bromo-6-hydroxynicotinate | HCID 2764315 | — |
| Reactant | HCID 21109696 | HCID 21109696 | — |
| Product | HCID 21109684 | HCID 21109684 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 102, using 5-bromo-6-hydroxy-nicotinic acid methyl ester, 2-methoxyethanol, (4-chloro-phenyl)-boronic acid and 2-(aminomethyl)-1-pentanol as starting materials to yield (RS)-5-(4-chloro-phenyl)-N-(2-hydroxymethyl-pentyl)-6-(2-methoxy-ethoxy)-nicotinamide. MS (ISP) 407.5 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07229999B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-832df8b7fb604bf7b19bcccb5d1d70cc |
| Source note | uspto-grants-2007_06 |