HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenylboronic acid → HCID 11950413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | (1-methyl-1H-imidazol-2-yl)methanol | HCID 573612 | — |
| Reactant | Methyl 5-bromo-6-chloronicotinate | HCID 2764313 | — |
| Reactant | cis-2-Aminomethyl-1-cyclohexanol | HCID 12483365 | — |
| Product | HCID 11950413 | HCID 11950413 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 102, using 5-bromo-6-chloro-3-pyridinecarboxylic acid methyl ester, 1-methyl-1H-imidazole-2-methanol, (4-chloro-phenyl)-boronic acid and cis-2-aminomethyl-1-cyclohexanol as starting materials to yield racemic cis-5-(4-chloro-phenyl)-N-(2-hydroxy-cyclohexylmethyl)-6-(1-methyl-1H-imidazol-2-ylmethoxy)-nicotinamide, MS (ISP) 455.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07229999B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-609ee36344164f09b1ca9fb1f163614e |
| Source note | uspto-grants-2007_06 |