HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenylboronic acid → HCID 11950589, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| Reactant | (1R,2R)-2-Aminocyclohexanol | HCID 735777 | — |
| Reactant | 2-Pyrimidinemethanol | HCID 2763024 | — |
| Product | HCID 11950589 | HCID 11950589 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 75, using 5-bromo-6-chloro-3-pyridinecarboxylic acid, 2-pyrimidinemethanol, (4-chloro-phenyl)-boronic acid and ((1R,2R)-2-amino-1-cyclohexanol as starting materials to yield 5-(4-chloro-phenyl)-N-((1R,2R)-2-hydroxy-cyclohexyl)-6-(pyrimidin-2-ylmethoxy)-nicotinamide, MS (ISP) 439.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07229999B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-3744b2f03f9e471f92b3a2b98e104126 |
| Source note | uspto-grants-2007_06 |