HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxymethylpyridine → HCID 67011859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxymethylpyridine | HCID 11472 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| Reactant | cis-2-Aminomethyl-1-cyclohexanol | HCID 12483365 | — |
| Product | HCID 67011859 | HCID 67011859 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 75, using 5-bromo-6-chloro-3-pyridinecarboxylic acid, 4-pyridinemethanol, (4-chloro-phenyl)-boronic acid and cis-2-aminomethyl-1-cyclohexanol as starting materials to yield cis-5-(4-chloro-phenyl)-N-(2-hydroxy-cyclohexylmethyl)-6-(pyridin-4-ylmethoxy)-nicotinamide, MS (ISP) 452.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07229999B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-0868983c69b9405d9ae705f63ecd8930 |
| Source note | uspto-grants-2007_06 |