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HRID1766546

反应详情

EQUATION

反应方程式

HRID 1766546 的结构方程式

REACTANTS

反应物

4
结构：OCc1ccncc1
HCID11472

4-Pyridinemethanol

C6H7NO

结构：OB(O)c1ccc(Cl)cc1
HCID74299

Benzeneboronic acid, p-chloro-

C6H6BClO2

结构：O=C(O)c1cnc(Cl)c(Br)c1
HCID285433

5-bromo-6-chloronicotinic acid

C6H3BrClNO2

结构：CCC(CN)CO
HCID15356533

未命名化合物

PRODUCTS

生成物

1
结构：CCC(CO)CNC(=O)c1cnc(OCc2ccncc2)c(-c2ccc(Cl)cc2)c1
HCID21109627

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 75, using 5-bromo-6-chloro-3-pyridinecarboxylic acid, 4-pyridinemethanol, (4-chloro-phenyl)-boronic acid and 2-aminomethyl-1-butanol as starting materials to yield racemic 5-(4-chloro-phenyl)-N-(2-hydroxymethyl-butyl)-6-(pyridin-4-ylmethoxy)-nicotinamide, MS (ISP) 426.1 (M+H)+.

WORKUP

后处理

  1. customThe title compound was synthesized in analogy to Example 75