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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766555Generated: November 2, 2026

3-Pyridinemethanol → HCID 67012376, compound

https://huagongshe.com/reaction/1766555

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PyridinemethanolHCID 7510—
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant5-Bromo-6-chloropyridine-3-carboxylic acidHCID 285433—
Reactant(1R,2R)-2-AminocyclohexanolHCID 735777—
ProductHCID 67012376HCID 67012376—

Reaction Steps

The title compound was synthesized in analogy to Example 75, using 5-bromo-6-chloro-3-pyridinecarboxylic acid, 3-pyridinemethanol, (4-chloro-phenyl)-boronic acid and ((1R,2R)-2-amino-1-cyclohexanol as starting materials to yield 5-(4-chloro-phenyl)-N-((1R,2R)-2-hydroxy-cyclohexyl)-6-(pyridin-3-ylmethoxy)-nicotinamide, MS (ISP) 438.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07229999B2
Source datasetuspto-grants-2007_06
ORD IDord-26520b5670834352bc83f922cd81f412
Source noteuspto-grants-2007_06