(3-Methoxybenzyl) triphenylphosphonium bromide → HCID 69427784, compound

HRID 1766654Notes

Reaction equation

HRID 1766654 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[C:20]([CH3:21])=[CH:19][C:18]([N+:22]([O-:24])=[O:23])=[C:17]3[C:13]=2[CH2:14][CH2:15][CH2:16]3)=[CH:7][C:4]=1[CH:5]=O.[Br-].[CH3:26][O:27][C:28]1[CH:29]=[C:30]([CH:51]=[CH:52][CH:53]=1)[CH2:31][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[C:20]([CH3:21])=[CH:19][C:18]([N+:22]([O-:24])=[O:23])=[C:17]3[C:13]=2[CH2:14][CH2:15][CH2:16]3)=[CH:7][C:4]=1[CH:5]=[CH:31][C:30]1[CH:51]=[CH:52][CH:53]=[C:28]([O:27][CH3:26])[CH:29]=1

Participants

3

Reactant 2

HCID 23031204(3-Methoxybenzyl) triphenylphosphonium bromideHCID 230312052-Methoxy-5-(5-methyl-7-nitroindan-4-yloxy)benzaldehyde

Product 1

HCID 69427784HCID 69427784, compound

Procedure

4-{4-Methoxy-3-[2-(3-methoxyphenyl)vinyl]phenoxy}-5-methyl-7-nitroindane was prepared in a similar manner to those described in Reference Example 15 using 2-methoxy-5-(5-methyl-7-nitroindan-4-yloxy)benzaldehyde instead of 2-benzyloxy-5-(5-methyl-7-nitroindan-4-yloxy)benzaldehyde and using (3-methoxybenzyl) triphenylphosphonium bromide instead of furfuryltriphenylphosphonium bromide.

Sources & evidence

ORD record
ord-ab59a7b92dc64b03ac13eff27eb67645
Source dataset
uspto-grants-2007_06
Patent number
US07230031B2

Reaction notes

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