HCID 21110579, compound → HCID 23031242, compound

HRID 1766679Notes

Reaction equation

HRID 1766679 reaction equation
C([O:8][C:9]1[CH:28]=[CH:27][C:12]([O:13][C:14]2[C:22]([CH3:23])=[CH:21][C:20]([N+:24]([O-])=O)=[C:19]3[C:15]=2[CH2:16][CH2:17][CH2:18]3)=[CH:11][C:10]=1[CH2:29][C:30]1[CH:35]=[CH:34][C:33]([F:36])=[CH:32][CH:31]=1)C1C=CC=CC=1>[Pd]>[NH2:24][C:20]1[CH:21]=[C:22]([CH3:23])[C:14]([O:13][C:12]2[CH:27]=[CH:28][C:9]([OH:8])=[C:10]([CH2:29][C:30]3[CH:31]=[CH:32][C:33]([F:36])=[CH:34][CH:35]=3)[CH:11]=2)=[C:15]2[C:19]=1[CH2:18][CH2:17][CH2:16]2

Participants

3

Reactant 1

HCID 21110579HCID 21110579, compound

Product 1

HCID 23031242HCID 23031242, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared in a similar manner to those described in Reference Example 34 using 4-[4-benzyloxy-3-(4-fluorobenzyl)phenoxy]-5-methyl-7-nitroindane instead of 4-(4-benzyloxy-3-iodophenoxy)-5-methyl-7-nitroindane and using Pd/C instead of Pt/C.

Sources & evidence

ORD record
ord-e12577a7b5874dac8967e1df38f84b3c
Source dataset
uspto-grants-2007_06
Patent number
US07230031B2

Reaction notes

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