Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Oxalate | HCID 7268 | — |
| Reactant | HCID 23031084 | HCID 23031084 | — |
| Product | HCID 21110635 | HCID 21110635 | 93.5% |
Reaction Steps
To 4-(7-amino-5-methylindan-4-yloxy)-2-ethyl-3-methylphenol (12 mg) was added diethyl oxalate (150 mg), and the mixture was stirred under an argon atmosphere at 120° C. for 3 hours. The reaction mixture was purified by thin layer chromatography on silica gel (developing solvent: hexane/ethyl acetate=2/1) to give the title compound (15 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07230031B2 |
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| Source dataset | uspto-grants-2007_06 |
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| ORD ID | ord-bfadfe816abe473fa75eb12b46690e87 |
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| Source note | uspto-grants-2007_06 |
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