Ethyl bromoacetate → HCID 86597601, compound

HRID 1766693Notes

Reaction equation

[CH2:1]([O:8][C:9]1[CH:26]=[CH:25][C:12]([O:13][C:14]2[C:22]3[CH2:21][CH2:20][CH2:19][C:18]=3[C:17]([OH:23])=[CH:16][C:15]=2[CH3:24])=[CH:11][C:10]=1[CH2:27][C:28]1[CH:33]=[CH:32][C:31]([F:34])=[CH:30][CH:29]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:36][C:37]([O:39][CH2:40][CH3:41])=[O:38]>>[CH2:1]([O:8][C:9]1[CH:26]=[CH:25][C:12]([O:13][C:14]2[C:15]([CH3:24])=[CH:16][C:17]([O:23][CH2:36][C:37]([O:39][CH2:40][CH3:41])=[O:38])=[C:18]3[C:22]=2[CH2:21][CH2:20][CH2:19]3)=[CH:11][C:10]=1[CH2:27][C:28]1[CH:33]=[CH:32][C:31]([F:34])=[CH:30][CH:29]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 7748Ethyl bromoacetate

HCID 21110597HCID 21110597, compound

Product 1

HCID 86597601HCID 86597601, compound

Procedure

The title compound was prepared in a similar manner to those described in Reference Example 11 using 7-[4-benzyloxy-3-(4-fluorobenzyl)phenoxy]-6-methylindan-4-ol instead of 2-hydroxy-5-(5-methyl-7-nitroindan-4-yloxy) benzaldehyde and using ethyl bromoacetate instead of benzyl bromide.

Sources & evidence

ORD record: ord-a668386278c7448bbc4f90a5b093fb73
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07230031B2

Reaction notes

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