3,4,5-Trimethoxybenzaldehyde → 3,4,5-Trimethoxytoluene

HRID 1766697Notes

Reaction equation

HRID 1766697 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:13][CH3:14])[C:10]=1[O:11][CH3:12])[CH:6]=O>C(O)(=O)C.[Pd]>[CH3:14][O:13][C:9]1[CH:8]=[C:5]([CH3:6])[CH:4]=[C:3]([O:2][CH3:1])[C:10]=1[O:11][CH3:12]

Participants

4

Reactant 1

HCID 68583,4,5-Trimethoxybenzaldehyde

Product 1

HCID 809223,4,5-Trimethoxytoluene

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

Synthesis, Volume 8 (1993), page 799 discloses hydrogenating 3,4,5-trimethoxybenzaldehyde, dissolved in acetic acid, in the presence of 10% palladium on activated carbon to give 3,4,5-trimethoxytoluene.

Sources & evidence

ORD record
ord-94ed31bcc04849299da09c0164605408
Source dataset
uspto-grants-2007_06
Patent number
US07230141B2

Reaction notes

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