Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1766756Generated: October 27, 2026

3-(2,6-Dichlorobenzyloxy)-5-bromopyridin-2-amine → ethyl 5-{6-amino-5-[(2,6-dichlorobenzyl)oxy]pyridin-3-yl}-1H-indole-2-carboxylate

https://huagongshe.com/reaction/1766756

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,6-Dichlorobenzyloxy)-5-bromopyridin-2-amineHCID 21111487—
ReactantEthyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylateHCID 21111505—
Productethyl 5-{6-amino-5-[(2,6-dichlorobenzyl)oxy]pyridin-3-yl}-1H-indole-2-carboxylateHCID 10253528—

Reaction Steps

5-[6-Amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-1H-indole-2-carboxylic acid ethyl ester was prepared from 5-bromo-3-(2,6-dichloro-benzyloxy)-pyridin-2-ylamine and 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester following procedure 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07230098B2
Source datasetuspto-grants-2007_06
ORD IDord-a131e46d11b24c0586eb22ce1bd09b55
Source noteuspto-grants-2007_06