1,3-Dihydro-5-(2-chlorophenyl)-2H-1,4-benzodiozepin-2-one → 1,3-dihydro-5-(o-bromophenyl)-2H-1,4-benzodiazepin-2-one
Reaction equation
[Br:20][c:21]1[cH:22][cH:23][cH:24][cH:25][c:26]1[C:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][c:33]1[N+:34]([O-:35])=[O:36])=[O:37].[Cl:1][c:2]1[c:3]([C:8]2=[N:9][CH2:10][C:11](=[O:19])[NH:12][c:13]3[c:14]2[cH:15][cH:16][cH:17][cH:18]3)[cH:4][cH:5][cH:6][cH:7]1.[NH2:38][c:39]1[cH:40][cH:41][cH:42][cH:43][c:44]1[C:45]([c:46]1[cH:47][cH:48][cH:49][cH:50][c:51]1[Br:52])=[O:53]>>[c:2]1([Br:20])[c:3]([C:8]2=[N:9][CH2:10][C:11](=[O:19])[NH:12][c:13]3[c:14]2[cH:15][cH:16][cH:17][cH:18]3)[cH:4][cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-a835918ed0534fcd9824ac57f5c859a6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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